People's Health Press
ISSN 2096-2738 CN 11-9370/R
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Electronic Journal of Emerging Infectious Diseases ›› 2023, Vol. 8 ›› Issue (2): 82-85.doi: 10.19871/j.cnki.xfcrbzz.2023.02.018

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Research progress on gut microbiota dysbiosis in patients with pulmonary tuberculosis

Yang Shuqi1, Li Feng1,2   

  1. 1. Department of Respiratory Medicine, Shanghai Public Health Clinical Center,Fudan University, Shanghai 201508, China;
    2. Shanghai Institute of Major Infectious Diseases and Biosafety, Shanghai 200032, China
  • Received:2022-01-21 Online:2023-04-30 Published:2023-05-19

Abstract: Trillions of microorganisms are planted in the human intestine, and gut microbiota can protect the host from disease through derived metabolites. During the thousands of years of struggle between human and Mycobacterium tuberculosis, pulmonary tuberculosis has been confirmed to cause the host's gut microbiota dysbiosis, affect resistance to the colonization of gut microbiota, and make pulmonary tuberculosis more difficult to cure. This article summarized the latest research progress of the pulmonary microbiome, the impact of gut microbiome on the pulmonary microbiome, and the gut microbiota dysbiosis in patients with pulmonary tuberculosis.

Key words: Pulmonary tuberculosis, Gut microbiota, Fecal microbiota transplantation, Lung microbiota

CLC Number: