Abstract: Acquired Immunodeficiency Syndrome Professional Group, Society of Infectious Diseases, Chinese Medical Association, formulated the "Chinese guidelines for the diagnosis and treatment of AIDS" (here in after referred to as the "Guidelines") in 2005. The 2024 edition of the Guidelines was revised based on the 5th edition published in 2021, taking into account the latest research progress both domestically and internationally. The new edition of the Guidelines focuses on updating aspects such as antiviral therapy, comprehensive management, opportunistic infections, AIDS-related tumors, prevention and intervention of HIV infection, and introduces new content on "immunological non-responder (INR)". It also introduces the concept of "vulnerable populations with AIDS" for the first time, and adds recommendations for diagnosis and treatment along with the supporting evidence and strength of recommendation.The Guidelines encompass 14 aspects including epidemiology, characteristics of the pathogen, laboratory testing, disease mechanism, clinical manifestations and staging, diagnostic criteria, common opportunistic infections, antiviral therapy, immune reconstitution inflammatory syndrome, INR, AIDS-related tumors, prevention of mother-to-child transmission of HIV and reproductive planning for serodiscordant couples, pre- and post-exposure prophylaxis and prevention of HIV, and comprehensive management of HIV infection. These Guidelines aim to assist clinicians in making reasonable decisions regarding the diagnosis and management of AIDS, and will be regularly updated and revised according to research advancements at home and abroad.

Key words: Acquired immunodeficiency syndrome, Human immunodeficiency virus, Diagnosis, Treatment, Guidelines