Pulmonary CT findings for AIDS patients concomitant with multi-drug resistance tuberculosis

doi:10.19871/j.cnki.xfcrbzz.2021.01.006

Abstract

Abstract: Objective To investigate the CT features of multi- drug resistant tuberculosis(MDR-TB) in AIDS patients and in non-AIDS patients. and conduct comparative analysis to provide evidence for its clinical diagnosis and treatment. Method From December 2014 to April 2019, 25 cases of AIDS complicated with MDR-TB diagnosed in the Fourth People's Hospital of Nanning were collected as the observation group, and 50 cases of non AIDS patients with MDR-TB as the control group. Comparative analysis in CT manifestations of AIDS with MDR-TB and non-AIDS patients with MDR-TB were performed. Results In terms of lung field distribution, lesions in both of these two groups were mainly distributed in the whole lung of the two lungs with no statistically significant difference between two groups (15/25 vs 33/50, P>0.05). Regarding lesion morphology, the incidences of miliary and ground glass appearance in the observation group were significantly higher than those in the control group, while the incidences of nodular, patchy, spotty, streak appearance, caseous pneumonia/lung damage, calcification and cavity were significantly lower in the observation group than those in the control group (P<0.05). As for extrapulmonary manifestations, the incidence of pericardial effusion, mediastinal/hilar lymph node enlargement and tuberculosis in other parts of the body in the observation group was significantly higher than that of the control group, while the incidence of hilar mediastinal/lymph node calcification and pleural thickening was significantly lower than that of the control group(P<0.05), There was no significant difference in the occurrence of pleural effusion between the two groups (P<0.05). Conclusion The CT imaging findings of AIDS complicated with MDR-TB showed that the lesions had a wide range of distribution and usually involved the whole lung field.In terms of the morphology of the lesions, the ground glass appearance and the grainy appearance were the most characteristic changes of the lesions that were different from those of non-AIDS MDR-TB, and were more likely to be associated with mediastinal/hilar lymph node enlargement, pericardial thickening/pericardial effusion and pleural effusion.

Key words: Acquired immune deficiency syndrome, Multidrug resistant tuberculosis, Tomography, X-ray computer

Li Yu, Liu Xia, Zhou Jingru, Zou Jun, Lu Yibo. Pulmonary CT findings for AIDS patients concomitant with multi-drug resistance tuberculosis[J]. Electronic Journal of Emerging Infectious Diseases, 2021, 6(1): 27-30.

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