Abstract: Objective To investigate the clinical efficacy and safety of Qingre Jiedu prescription on patients with fatty metabolic syndrome after anti-viral treatment of AIDS. Methods 105 AIDS patients with dyslipidemia syndrome after antiviral treatment were randomly divided into treatment group A (Qingre Jiedu recipe), treatment group B (Jianpi Huashi formula) and control group C (placebo). After 12 weeks of treatment, the changes of serum TC, TG, LDL, HDL, B-ultrasound imaging appearance and the improvement of traditional Chinese medicine (TCM) related symptoms were obtained. Results After 12 weeks of treatment, the improvement of TCM related clinical symptoms, serum TC, TG, LDL-C and HDL-C, abdominal B-ultrasound imaging findings of treatment group A and B were significantly better than those of the control group, while the differences of serum TC and B-ultrasound imaging findings between treatment group A and group B were statistically significant. Conclusion To a certain extent, the short-term clinical efficacy of Qingre Jiedu prescription on patients with fatty metabolic syndrome after anti-viral treatment of AIDS is better than that of conventional Jianpi Huashi prescription.

Key words: Acquired immune deficiency syndrome, Antiviral therapy, Dyslipidemia syndrome, Heat clearing and detoxification