Abstract: Objective To explore the clinical characteristics and CT findings of AIDS-related abdominal lymphoma, enhance the understanding of AIDS-related abdominal lymphoma, and provide evidence for clinical diagnosis and treatment. Methods The clinical characteristics and CT findings of 39 patients with AIDS-related abdominal lymphoma confirmed by pathology were retrospectively analyzed. Results 1 of 39 cases of HIV/AIDS with abdominal lymphoma was associated with Hodgkin's lymphoma, and the other 38 cases were non-hodgkin's lymphoma cases.The main finding is the presence of multiple enlarged lymph nodes with high rate of extra-lymph node involvement (27/39, 69.23%). All the extra-lymph node involvements include liver (n=11), pancreas and stomach (both n=8), spleen, intestines, and adrenal gland (n=4), kidney（n=3）, bladder, uterus and testes (all n=2), and prostate gland (n=1). The lesions were mostly manifested as soft tissue masses with reduced density, often piled or fused into masses, with central liquefaction and necrosis. Conclusion AIDS-related abdominal lymphoma is mainly non-Hodgkin's lymphoma, which is highly invasive, extensively involving abdominal lymph nodes and organs other than lymph nodes, and has a high incidence of extra-lymph node involvement. CT findings were characteristic to some extent, and if combined with clinical manifestations, could improve the diagnostic match rate.

Key words: Acquired immune deficiency syndrome, Lymphoma, Abdomen, Computed tomography findings