重庆万州地区男男性行为人群HIV感染情况及其危险因素分析

doi:10.19871/j.cnki.xfcrbzz.2021.04.018

新发传染病电子杂志 ›› 2021, Vol. 6 ›› Issue (4): 343-347.doi: 10.19871/j.cnki.xfcrbzz.2021.04.018

重庆万州地区男男性行为人群HIV感染情况及其危险因素分析

刘鑫, 陈永宏, 陈瑞华, 田冰, 赵春娥

重庆大学附属三峡医院感染科, 重庆万州 404000

收稿日期:2020-12-31 出版日期:2021-11-30 发布日期:2021-12-13
通讯作者: 赵春娥,Email: 13637841997@139.com
基金资助:
重庆市卫生计生委中医药科技项目（ZY201703067）; 重庆市万州区科学技术项目（201403016）

Analysis of HIV infection and risk factors among men who have sex with men in Wanzhou, Chongqing

Liu Xin, Chen Yonghong, Chen Ruihua, Tian Bing, Zhao chun'e

Department of Infectious Diseases, Three Gorges Hospital Affiliated to Chongqing University, Chongqing Wanzhou 404000, China

Received:2020-12-31 Online:2021-11-30 Published:2021-12-13

摘要/Abstract

摘要： 目的对重庆万州地区男男性行为（MSM）人群HIV感染情况进行调查,并分析其危险因素。方法 2020年1–12月在重庆万州地区通过同伴介绍、社会组织外展干预转介、QQ群、微信群等社交平台宣传方式招募在1年内有插入性口交或肛交同性性行为的男性349例进行调查。通过问卷收集可能影响MSM人群HIV感染的因素,对所有调查对象进行抽血检验,根据HIV感染情况将调查对象分为HIV阳性组与HIV阴性组,比较两组调查对象经问卷收集的各因素,并采用多因素Logistic回归分析判断各因素对MSM人群感染HIV的综合影响。结果本次调查共发放问卷349份,回收有效问卷342份,回收有效率为97.99%。在有效调查对象中共有21例（6.14%）被确诊为HIV感染。多因素Logistic回归分析结果显示：年龄增加（OR=1.436,95%CI=1.015~2.032）、有饮酒史（OR=1.446,95%CI=1.053~1.987）、有吸毒史（OR=1.517,95%CI=1.081~2.130）、性角色为0号（OR=1.536,95%CI=1.129~2.089）,近6个月性行为时偶尔使用或不使用安全套（OR=1.505,95%CI=1.075~2.109）、近6个月有商业性行为史（OR=1.465,95%CI=1.040~2.065）、有性病史（OR=1.670,95%CI=1.165~2.396）、性伴人数>1位（OR=1.525,95%CI=1.045~2.226）、使用助性剂（OR=1.507,95%CI=1.042~2.178）为重庆万州地区MSM人群HIV感染的危险因素（均P<0.05）。结论重庆万州地区MSM人群HIV感染率较高,此类人群HIV感染主要受年龄、文化程度、饮酒史等因素的影响,可根据上述因素进行针对性干预以降低MSM人群的HIV感染率。

关键词: 男男性行为人群, 人类免疫缺陷病毒感染, 危险因素

Abstract: Objective To investigate the HIV infection among men who have sex with men (MSM) in Wanzhou, Chongqing, and analyze its risk factors. Methods From January to December 2020, 349 men with same-sex sexual behavior of oral or anal sex within one year were recruited in Wanzhou, Chongqing were recruited through peer introduction, social organization outreach intervention and referral, QQ group, wechat group and other social platforms. Collect the factors that may affect the HIV infection of MSM population through questionnaire, take blood test for all respondents, and divide the respondents into HIV positive group and HIV negative group according to the HIV infection.The factors collected by the questionnaire were compared between the two groups of survey subjects, and the multi-factor Logistic regression analysis was used to determine the comprehensive impact of each factor on the HIV infection in the MSM population. Results 349 questionnaires were distributed and 342 valid questionnaires were recovered, with a recovery rate of 97.99%. A total of 21 people (6.14%) were diagnosed with HIV infection. Multivariate Logistic regression analysis showed that age（OR=1.436,95%CI=1.015~2.032）, drinking history（OR=1.446,95%CI=1.053~1.987）, drug use history（OR=1.517,95%CI=1.081~2.130 ）, sex role No.0（OR=1.536,95%CCI=1.129~2.089）, occasional condom use or no condom use in recent 6 months（OR=1.505,95%CI=1.075~2.109）, commercial sex history in recent 6 months（OR=1.465,95%CI=1.040~2.065）, sexual history（OR=1.670,95%CI=1.165~2.396）, number of sexual partners >1（OR=1.525,95%CI=1.045~2.226）, and use of booster（OR=1.507,95%CI=1.042~2.178）were risk factors for HIV infection among MSM in Wanzhou, Chongqing (P<0.05). Conclusion The HIV infection rate of MSM population in Wanzhou, Chongqing is high. The HIV infection of this population is mainly affected by age, education level, drinking history and other factors. Targeted intervention can be carried out according to the above factors to reduce the HIV infection rate of MSM population.

Key words: Men who have sex with men, HIV infection, Risk factor

刘鑫, 陈永宏, 陈瑞华, 田冰, 赵春娥. 重庆万州地区男男性行为人群HIV感染情况及其危险因素分析[J]. 新发传染病电子杂志, 2021, 6(4): 343-347.

Liu Xin, Chen Yonghong, Chen Ruihua, Tian Bing, Zhao chun'e. Analysis of HIV infection and risk factors among men who have sex with men in Wanzhou, Chongqing[J]. Electronic Journal of Emerging Infectious Diseases, 2021, 6(4): 343-347.

参考文献

[1] 杨娟,徐慧芳,程伟彬, 等.男男性行为人群个体社会网络中关系强度及其相关因素分析[J].中华流行病学杂志,2018,39(4):478-482.
[2] SULLIVAN PS, PURCELL DW, GREY JA, et al.Patterns of Racial/Ethnic Disparities and Prevalence in HIV and Syphilis Diagnoses Among Men Who Have Sex With Men, 2016: A Novel Data Visualization[J]. Am J Public Health, 2018, 108(S4):266-273.
[3] LI SX, SEN S, SCHNEIDER JM, et al.Gut microbiota from high-risk men who have sex with men drive immune activation in gnotobiotic mice and in vitro HIV infection[J]. PLos Pathogs, 2019, 15(4): 1007611-1007614.
[4] 杨茂瑜,郎中凯.重庆市万州区2012年不同人群HIV抗体检测结果分析[J].中国卫生检验杂志,2014,24(3):406-407.
[5] 胡虹, 韩孟杰, 吕柯, 等. 利用《中国艾滋病防治督导与评估框架(试行)》指标评价中国艾滋病防治工作[J]. 中国艾滋病性病, 2010, 16(3):286-287.
[6] SARIKA P, HOLTZ TH, CHAIWAT U, et al.Repeat symptomatic Neisseria gonorrhoeae infections among men who have sex with men in Bangkok, Thailand, 2006-2016[J]. Int J STD AIDS, 2020,31(6):533-540.
[7] DINENNO E A, PREJEAN J, IRWIN K, et al.Recommendations for HIV screening of gay, bisexual, and other men who have sex with men—United States, 2017[J]. MMWR-Morbid Mortal W, 2017, 66(31): 830-833.
[8] HOAGLAND B, MOREIRA RI, DEBONI RB, et al.High pre‐exposure prophylaxis uptake and early adherence among men who have sex with men and transgender women at risk for HIV Infection: the PrEP Brasil demonstration project[J]. J Int AIDS Soc, 2017, 20(1): 21472-21477.
[9] 张维,卢戎戎,吴国辉.重庆市艾滋病疫情网络直报数据库老年人HIV/AIDS特征分析[J].重庆医学,2017,46(6):815-817.
[10] 蔡于茂, 宋亚娟, 刘惠,等. 2011—2016年深圳市男男性行为人群梅毒和HIV感染情况及影响因素[J]. 中华预防医学杂志, 2017, 51(11):994-1000.
[11] 冯娟. 安阳地区无偿献血者及其中男男性行为人群HIV感染情况调查分析[J]. 安徽医学, 2018, 2(39):70-73.
[12] 蔡于茂, 宋亚娟, 潘鹏,等. 男男性行为者梅毒合并HIV感染影响因素分析[J]. 中国公共卫生, 2013, 29(8):1127-1130.
[13] QUEIROZ A, DESOUAS ÁF, DEARAÚJO T, et al. A review of risk behaviors for HIV infection by men who have sex with men through geosocial networking phone apps[J]. J Assoc Nurse AIDS C, 2017, 28(5): 807-818.
[14] FINLAYSON T, CHA S, XIA M, et al.Changes in HIV preexposure prophylaxis awareness and use among men who have sex with men—20 urban areas, 2014 and 2017[J]. Morbid Mortal W Rep, 2019, 68(27): 597-603.
[15] MITSCH A, SINGH S, LI J, et al.Age-associated trends in diagnosis and prevalence of infection with HIV among men who have sex with men—United States, 2008-2016[J]. Morbid Mortal W Rep, 2018, 67(37): 1025-1029.
[16] KROON E, PHANUPHAK N, SHATTOCK AJ, et al.Acute HIV infection detection and immediate treatment estimated to reduce transmission by 89% among men who have sex with men in Bangkok[J]. J Int AIDS Soc, 2017, 20(1): 21708.
[17] PAKIANATHAN M, WHITTAKER W, LEE MJ, et al.Chemsex and new HIV diagnosis in gay, bisexual and other men who have sex with men attending sexual health clinics[J]. HIV Med, 2018, 19(7): 485-490.
[18] GARNER W, WILSON BM, BESTE L, et al.Gaps in Preexposure Prophylaxis Uptake for HIV Prevention in the Veterans Health Administration[J]. Am J Public Health, 2018, 108(4):305-310.
[19] SIEGLER AJ, FARAH M, MERA GR, et al.The prevalence of pre-exposure prophylaxis use and the pre-exposure prophylaxis-to-need ratio in the fourth quarter of 2017, United States[J]. Ann Epidemiol, 2019, 28(12):841-849.
[20] ZIOGA E, TORRE A, PATERA E, et al.The role of biomedical interventions in HIV prevention: Pre-exposure Prophylaxis (PrEP)[J]. Semergen, 2020,46(3):202-207.
[21] 祁慧,王敏,游霞,等.男男性行为HIV/AIDS患者抑郁症及相关因素研究[J/CD].新发传染病电子杂志,2019,4(4):220-222,239.

重庆万州地区男男性行为人群HIV感染情况及其危险因素分析

Analysis of HIV infection and risk factors among men who have sex with men in Wanzhou, Chongqing

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