SARS-CoV-2 omicron variant strains infection: comparative analysis of clinical features in moderate group and mild/asymptomatic group and chest CT findings

doi:10.19871/j.cnki.xfcrbzz.2022.02.002

Abstract

Abstract: Objective To investigate the differences of clinical characteristics in patients with SARS-CoV-2 omicron variant strains infection in different group and Chest CT imaging. Method A retrospective analysis of the clinical data of 68 patients with SARS-CoV-2 omicron variant infection was conducted. According to whether the patients had pneumonia or not, they were divided into moderate group and asymptomatic/mild group, the clinical manifestation differences between the two groups were compared, and the moderate group chest CT imaging characteristics were analyzed. Result Among the 68 cases of SARS-CoV-2 omicron variant infection, the main clinical manifestations were cough in 49 cases, pharyngeal discomfort in 27 cases, fever in 24 cases, and fatigue in 12 cases. The proportion of fever in the moderate group was higher than that in the asymptomatic/mild group, and the difference was statistically significant (P<0.05), the proportion of pre-existing diseases in the moderate group was higher than that of the asymptomatic/mild group, the difference was statistically significant (P<0.05), the peak ESR in the moderate group was higher than that of the asymptomatic/mild group, the difference was statistically significant (P<0.05), the difference of the lowest Ct value of nucleic acid was not statistically significant between the moderate group and asymptomatic/mild group. The common chest CT of omicron variant pneumonia was subpleural ground-glass opacity and consolidation. The percentage of pneumonia lesions to the whole lung volume showed an average of 2.2% (0.1%~12.2%) by chest CT. The average time from onset of symptoms to pneumonia peak is 8.6 days by chest CT. Conclusion The clinical symptoms of SARS-CoV-2 omicron variant infected patients are mild;fever, pre-existing diseases and ESR can be used as observation indicators. The damage to the lung by the virus is mild, and the chest CT mainly showed ground-glass opacity and consolidation with subpleural distribution.

Key words: Coronavirus disease 2019, Severe acute respiratory syndrome coronavirus 2, Chest, Radiography, X-ray, Nucleic acid, Artificial intelligence

Liu Wenhao, Yang Jinrong, Chen Yixin, Zhou Yun, Li Yinfeng, Yun Yongxing, Yang Gendong, Huang Hua. SARS-CoV-2 omicron variant strains infection: comparative analysis of clinical features in moderate group and mild/asymptomatic group and chest CT findings[J]. Electronic Journal of Emerging Infectious Diseases, 2022, 7(2): 6-10.

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