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ISSN 2096-2738 CN 11-9370/R
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Electronic Journal of Emerging Infectious Diseases ›› 2021, Vol. 6 ›› Issue (3): 242-246.doi: 10.19871/j.cnki.xfcrbzz.2021.03.017

• Original Articles • Previous Articles     Next Articles

Correlation between CT imaging and the degree of CD4+T lymphocyte reduction of complicated with miliary tuberculosis

Ren Rong, Cheng Xi, Liu Rongrong, Yuan Gongling, Liu Jing, Yao Wenyan, Li Min   

  1. Department of Radiology, The Affiliated Infectious Diseases Hospital of Soochow University, The Fifth People's Hospital of Suzhou, Jiangsu Suzhou 215000, China
  • Received:2021-04-22 Online:2021-08-31 Published:2021-10-11

Abstract: Objective To analyze the correlation between the CT signs of complicated with miliary tuberculosis and the degree of CD4+T lymphocytesreduction, to provide reference for clinical diagnosis and treatment of the disease. Methods Retrospective analysis of CT imaging and clinical characteristics of 49 patients with complicated with miliary tuberculosis admitted to Suzhou Fifth People's Hospital. According to the count of low CD4+T lymphocytes, the patients were divided into groups Ⅰ,Ⅱ, and Ⅲ (respectively 1~50, 51~100, 101~200 cells/μl), with the CT imagines analyzed. Results ①The incidence rate of〝three unevenness〞in the size, density and distribution of miliary nodules in groupⅠwas higher than that in groups Ⅱ and Ⅲ, and the difference was statistically significant (P<0.05). The incidence rate of patchy shadow, pleural effusion, pericardial effusion, mediastinal lymphadenopathy, combined mediastinotomy node tuberculosis and extra-pulmonary tuberculosis in group I were also higher than those in group Ⅱ and Ⅲ, and the differences were statistically significant (P<0.05). ②Among mediastinal lymph node tuberculosis patients, the incidence rate of lymph node enlargement at 2 R, 3 A zone and uneven or separated enhancement in groupⅠ was higher than that in groupⅡ, Ⅲ,the difference was statistically significant (P<0.05). ③Miliary nodules of 3 cases (6.1%) had been absorbed during 3 months, and 46 cases (93.9%) absorbed during 6-12 months or more. Most of them accompanied by vary developed lesions. Conclusion The lower the number of CD4+T lymphocytes, the size, density, and distribution of miliary nodules in CT images of combined with miliary tuberculosis are more uneven, and the incidence rates of mediastinal lymph node tuberculosis, extra-pulmonary tuberculosis, pleural effusion and pericardial effusion are higher.

Key words: Acquired immune deficiency syndrome, Tuberculosis, Lung, Tomography, Computer tomography, CD4+T lymphocytes