关键词: 人类免疫缺陷病毒, 心血管疾病, 多模态影像学, 超声心动图, 计算机断层扫描, 磁共振成像, 核医学

Abstract: As a major public health problem worldwide, HIV infection has posed a severe test to national health systems since its discovery. With the wide application of antiretroviral therapy (ART), the life cycle of HIV-infected patients has been significantly prolonged, and cardiovascular diseases (CVD) have gradually become one of the main causes of death and disability in this population. The pathological mechanism of HIV infection complicated with CVD is complex, the clinical manifestations are diverse and the early symptoms are not typical. The clinical diagnosis and treatment are difficult, so early accurate identification and intervention are particularly critical. Multimodal imaging integrates echocardiography, cardiac computed tomography, cardiac magnetic resonance, nuclear medicine and other imaging techniques, which breaks the limitations of single imaging method and can be comprehensively evaluated from anatomical structure, cardiac function and molecular level. This article reviews the research progress of multimodal imaging technology in HIV infection complicated with CVD, in order to provide reference for early diagnosis, clinical management and prognosis evaluation of the disease.

Key words: Human immunodeficiency virus, Cardiovascular disease, Multimodal imaging, Echocardiography, Computed tomography, Magnetic resonance imaging, Nuclear medicine