人民卫生出版社系列期刊
ISSN 2096-2738 CN 11-9370/R

中国科技核心期刊(中国科技论文统计源期刊)
2020《中国学术期刊影响因子年报》统计源期刊
美国化学文摘社(CAS)数据库收录期刊
日本科学技术振兴机构(JST)数据库收录期刊

新发传染病电子杂志 ›› 2021, Vol. 6 ›› Issue (4): 361-367.doi: 10.19871/j.cnki.xfcrbzz.2021.04.022

• 综述 • 上一篇    下一篇

HIV相关感觉神经病的研究进展

陈瑶1, 韩亚坤2, 吴强2, 何仁亮1,2   

  1. 1.广东医科大学第一临床医学院,广东 湛江 524023;
    2.深圳市第三人民医院麻醉科,广东 深圳 518112
  • 收稿日期:2021-07-10 出版日期:2021-11-30 发布日期:2021-12-13
  • 通讯作者: 何仁亮,Email:szherenliang@163.com;吴强,Email:wq2283@qq.com
  • 基金资助:
    广东省自然科学基金(2020A1515010159)

Research progress on HIV-associated sensory neuropathy

Chen Yao1, Han Yakun2, Wu Qiang2, He Renliang1,2   

  1. 1. The First Clinical College of Guangdong Medical University, Guangdong Zhanjiang 524023, China;
    2. Department of Anesthsiology, the Third People's Hospital of Shenzhen, Guangdong Shenzhen 518112, China
  • Received:2021-07-10 Online:2021-11-30 Published:2021-12-13

摘要: 感觉神经病是艾滋病患者常见的一种并发症,目前临床医生对人类免疫缺陷病毒(HIV)感觉神经病的临床表现和发生机制认识不足,以及缺乏相应的治疗手段,使得大多数患者无法得到有效的治疗。本文就HIV相关感觉神经病的危险因素、机制和治疗等相关进展进行综述,旨在提高医务人员对HIV相关感觉神经病的诊治水平。

关键词: 艾滋病, 感觉神经病, Wnt信号通路, 包膜糖蛋白

Abstract: Sensory neuropathyis a common complication in people living with human immunodeficiency virus. Currently, a great number of patients cannot get effective treatment due to the clinicians have insufficient understanding of the clinical manifestation and mechanism of HIV-associated sensory neuropathy (HIV-SN)and lack of treatment methods. This paper reviews the progress of the risk factors, mechanisms and treatment of HIV-SNin order to improve the diagnosis and treatment of HIV-SN.

Key words: Acquired immune deficiency syndrome, Sensory neuropathy, Wnt signaling pathway, Envelope glycoprotein