基于文献分析的耐多药肺结核影像学研究进展

doi:10.19871/j.cnki.xfcrbzz.2021.01.015

摘要/Abstract

摘要： 耐药结核病是由耐药结核分枝杆菌所引起的呼吸道传染病,严重威胁着人类健康,尤其是耐多药结核病（multidrug-resistant tuberculosis,MDR-TB）治疗效果差,因此,及时发现耐多药结核病可以使患者得到更好的管理和治疗。本文根据已发表的文献资料,于2019年10月搜索PubMed数据库,搜索关键字组合为 “(multidrug-resistant tuberculosis) AND (CT or radiograph or imaging or X-ray or computed tomography)”,同时搜索万方知识数据服务平台,搜索关键字组合为 “(耐多药肺结核)与(CT或放射或影像或X线 )”,对MDR-TB的影像学研究进展进行分析总结。结果发现,目前已发表的文献资料显示MDR-TB患者没有确定的胸部影像诊断依据,患者胸部X线和CT中出现肺空洞,尤其是空洞越大或空洞壁越厚,以及出现毁损肺影像表现时,影像医生应该怀疑MDR-TB可能。同时分析结果显示,CT是主要的影像学检查方法,X线有一定局限性,正电子发射体层摄影-计算机断层扫描（positron emission tomography-computed tomography, PET-CT）目前只适用于评估MDR-TB治疗。利用人工智能（artificial intelligence, AI）技术进行MDR-TB的辅助诊断将成为未来一个新的重点研究方向。

关键词: 结核病, 耐多药结核, 计算机断层扫描

Abstract: Drug-resistant tuberculosis is a respiratory infectious disease caused by drug-resistant Mycobacterium tuberculosis, which seriously threatens human health. The disease is poorly treated, especially multidrug-resistant tuberculosis (MDR-TB).Therefore, timely detection of MDR-TB can enable patients to be better managed and treated.Based on published literature, this article searches the PubMed database in October 2019. The search keyword combination is "(multidrug-resistant tuberculosis) AND (CT or radiograph or imaging or X-ray or computed tomography)", while searching Wanfang Medical database, the search keyword combination is "(multidrug-resistant tuberculosis) and (CT or radiology or imaging or X-ray)" to analyze and summarize the progress of MDR-TB in imaging research.The published literature shows that MDR-TB patients have no definite chest imaging diagnosis basis. When the chest X-ray and CT, the patient appears lung cavity, especially the larger the cavity or the thicker the cavity wall, the more prompt It is the possibility of MDR-TB, and the imaging doctor should doubt the possibility of MDR-TB when there is the appearance of damaged lung imaging.At the same time, the analysis results show that CT is the main imaging method, and X-rays have certain limitations. Positron Emission Tomography-Computed Tomography (PET-CT) is currently only applicable to assess MDR-TB treatment. The result description is not concise, you can refer to how other similar articles are described. Using artificial intelligence (AI) technology for MDR-TB auxiliary diagnosis will become a new key research direction in the future.

Key words: Tuberculosis, Multidrug-resistant tuberculosis, Computed tomography

马璐瑶, 郑秋婷, 陆普选, 李宏军, 刘远明, 殷小平, 郭琳. 基于文献分析的耐多药肺结核影像学研究进展[J]. 新发传染病电子杂志, 2021, 6(1): 65-72.

Ma Luyao, Zheng Qiuting, Lu Puxuan, Li Hongjun, Fleming YM Lure, Yin Xiaoping, Guo Lin. Pulmonary multi-drug resistant tuberculosis: a radiological review[J]. Electronic Journal of Emerging Infectious Diseases, 2021, 6(1): 65-72.

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