关键词: 肺结核, 肺通气功能障碍, 社区人群, 结核后肺疾病

Abstract: Objective To investigate the status of pulmonary ventilation dysfunction among community residents aged ≥40 years with prior pulmonary tuberculosis in Shenzhen, and to provide a reference basis for the early intervention of pulmonary ventilation dysfunction. Method Through multi-stage stratified cluster sampling, 4157 residents aged≥40 years were selected from 36 community survey sites in Shenzhen for questionnaire survey and pulmonary function tests, from September 2018 to June 2019. The demographic characteristics of the survey subjects were described as frequency and percentage. Their pulmonary ventilation function was further analyzed. Result A total of 3591 residents completed the questionnaire and pulmonary function tests. Among them, 66 participants had a history of pulmonary tuberculosis. The prevalence of pulmonary ventilation dysfunction in this group was 21.21% (14/66), which was significantly higher than that in participants without a history of pulmonary tuberculosis (11.55%, 407/3525; χ²= 5.85, P<0.05). Among participants with a history of pulmonary tuberculosis who had pulmonary ventilation dysfunction, 42.86% (6/14) had moderate or severe dysfunction, compared with 37.35% (152/407) in those without a history of pulmonary tuberculosis; the difference was not statistically significant (χ²= 2.22, P>0.05). Conclusion The subjects with prior pulmonary tuberculosis are more likely to have pulmonary ventilation dysfunction. For those with prior pulmonary tuberculosis, it is recommended to complete pulmonary function examination as soon as possible, to evaluate their lung condition. The early intervention can delay the occurrence of pulmonary ventilation dysfunction, and prevent the occurrence of post-tuberculosis pulmonary disease.

Key words: Pulmonary tuberculosis, Pulmonary ventilation dysfunction, Community population, Post-tuberculosis lung disease