人民卫生出版社系列期刊
ISSN 2096-2738 CN 11-9370/R

中国科技核心期刊(中国科技论文统计源期刊)
中国科学引文数据库(CSCD)来源期刊
《中国学术期刊影响因子年报》统计源期刊
美国化学文摘社(CAS)数据库收录期刊
日本科学技术振兴机构(JST)数据库收录期刊

新发传染病电子杂志 ›› 2025, Vol. 10 ›› Issue (3): 24-28.doi: 10.19871/j.cnki.xfcrbzz.2025.03.005

• 论著 • 上一篇    下一篇

疑似肺结核的机化性肺炎患者临床及病理特征分析

张琳, 肖海浩, 李天义, 苏雯婕   

  1. 广州市胸科医院结核内科,广东 广州 510095
  • 收稿日期:2025-02-27 出版日期:2025-06-30 发布日期:2025-07-24
  • 通讯作者: 李天义,Email:tianyi_mail@163.com
  • 基金资助:
    1.广东省医学科学技术研基金项目(C2022112);2.广州市临床高新、重大、特色技术建设项目(2023-2025)项目(2023C-TS30)(穗卫函【2023】268号);3.广州市医学重点学科(2025-2027年)结核病

Analysis of clinical and pathological characteristics of organizing pneumonia suspected of pulmonary tuberculosis

Zhang Lin, Xiao Haihao, Li Tianyi, Su Wenjie   

  1. Department of Internal Medicine-Tuberculosis, Guangzhou Chest Hospital, Guangdong Guangzhou 510095, China
  • Received:2025-02-27 Online:2025-06-30 Published:2025-07-24

摘要: 目的 分析疑似肺结核的机化性肺炎(organizing pneumonia,OP)患者的临床、病理特征,以及被误诊、漏诊的原因,提高OP临床早期确诊概率。方法 选取2019年1月至2023年3月广州市胸科医院收治的72例0P病例为研究组,同期收治的72例肺结核患者为对照组,比较两组患者的基础病史、临床及胸部CT表现、病理学改变等资料。结果 72例OP患者的基础病史,咳嗽、发热、胸痛、肺部啰音等临床表现及胸部CT表现与肺结核患者相似;72例OP患者肺部病理改变具有显著特异性:肺泡内、肺泡管内、呼吸性细支气管内间质纤维肉芽组织明显增生,呈息肉样增生突入肺泡腔。结论 OP患者的基础病史、临床及胸部CT表现缺乏特异性,易被误诊、漏诊为肺结核,应高度重视OP肺部病理性改变,才能有助于早期识别OP。

关键词: 机化性肺炎, 诊断, 肺结核, 临床研究

Abstract: Objective To analyze the clinical and pathological characteristics of patients with organizing pneumonia suspected of pulmonary tuberculosis and the cause of misdiagnosed and missing, in order to improve the early clinical diagnosis rate of organizing pneumonia. Method The data of 72 cases of organizing pneumonia patients and 72 cases of pulmonary tuberculosis patients admitted to Guangzhou Chest Hospital from January 2019 to March 2023 were collected. The basic medical history, clinical manifestations, chest CT findings, pathological changes and other data were statistically analyzed. Result 72 cases of organizing pneumonia were similar to pulmonary tuberculosis in the risk factor clinical manifestations such as cough, fever, chest pain, pulmonary rales and imaging data, but it had obvious specificity in pathological changes:there was obvious hyperplasia of interstitial fibrous granulation tissue in alveoli, and a polypoid hyperplasia protruding into the alveolar cavity. Conclusion The risk facto clinical manifestations and imaging data of the organizing pneumonia patients lacked specificity, it is easy to be mistaken and misdiagnosed as pulmonary tuberculosis, attention should be paid to the differences between the two diseases, to help early diagnosis of organizing pneumonia.

Key words: Organizing pneumonia, Diagnosis, Pulmonary tuberculosis, Clinical study

中图分类号: