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新发传染病电子杂志

新发传染病电子杂志 ›› 2025, Vol. 10 ›› Issue (2): 14-18.doi: 10.19871/j.cnki.xfcrbzz.2025.02.003

• 论著 • 上一篇    下一篇

基于超声彩色多普勒技术对布鲁氏菌病患者急性发作与肌腱及周围滑膜血流信号的相关性研究

武国华1, 祁秀2, 康孚嘉1, 郭芳芳1, 苏玉梅3, 张书毓4, 栗平1   

  1. 1.内蒙古医科大学第二附属医院超声科, 内蒙古 呼和浩特 010000;
    2.呼和浩特市第二医院超声科, 内蒙古 呼和浩特 010000;
    3.乌兰察布市中心医院超声科, 内蒙古 乌兰察布 012000;
    4.内蒙古医科大学研究生院, 内蒙古 呼和浩特 010000
  • 收稿日期:2024-10-21 发布日期:2025-06-16
  • 通讯作者: 栗平,Email：liPing5767@sina.com
  • 基金资助:
    内蒙古自治区自然科学基金项目（2023LHMS08053）

A study on the correlation between acute episodes of brucellosis and blood flow signals in tendons and surrounding synovium based on color doppler ultrasonography

Wu Guohua1, Qi Xiu2, Kang Fujia1, Guo Fangfang1, Su Yumei3, Zhang Shuyu4, Li Ping1   

  1. 1. Second Affiliated Hospital of Inner Mongolia Medical University Ultrasound Department, Inner Mongolia Hohhot 010000, China;
    2. The Second Hospital of Hohhot Ultrasound Department, Inner Mongolia Hohhot 010000, China;
    3. Ulanqab Central Hospital Ultrasound Department, Inner Mongolia Ulanqab 012000, China;
    4. Graduate School of Inner Mongolia Medical University, Inner Mongolia Hohhot 010000, China
  • Received:2024-10-21 Published:2025-06-16

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摘要： 目的 本研究旨在探究布鲁氏菌病急性发作与肌腱或周围滑膜血流信号之间的相关性,评估肌肉骨骼超声彩色多普勒技术在判断布鲁氏菌是否处于急性发作期的潜力。方法 纳入2023年8月至2024年4月于呼和浩特市第二医院诊断患有布鲁氏菌病的患者90例,根据是否发热及实验室检查结果分为急性发作组和非急性发作组。所有病例行肌骨超声彩色多普勒技术检查,观察肌腱和周围滑膜的血流信号,并进行统计分析。结果 布鲁氏菌病急性发作组56例（62.2%）,其中病灶血流信号增多者19例（33.9%）,无明显血流信号者37例（66.1%）;非急性发作组34例（37.8%）,其中血流信号增多者4例（11.8%）,无明显血流信号者30例（88.2%）。比较急性发作组和非急性发作组患者的影像学特点,两组间肌腱或滑膜血流信号存在显著差异（P=0.019）。急性发作与血流信号的Phi系数为0.246,表现为一定程度上的正相关（P=0.019）。单因素Logistic回归分析发现血流信号增多的病例处在急性发作期的概率是无明显血流信号组的3.851倍（P=0.025）。结论 肌腱或周围滑膜的血流信号增加与布鲁氏菌病急性发作有一定程度的相关性,可与临床其他诊断指标相结合成为诊断布鲁氏菌病急性发作期的有效补充手段,肌肉骨骼超声彩色多普勒成像有望作为评估布鲁氏菌病急性发作期的辅助诊断技术之一,为临床医师提供更准确的诊断和管理策略的指导。

关键词: 布鲁氏菌病, 肌骨超声检查, 炎症急性期活动指标, 软组织血流信号

Abstract: Objective This study aims to investigate the correlation between acute episodes of brucellosis and increased blood flow signals in tendons or surrounding synovial membranes, evaluating the potential of musculoskeletal ultrasound with color Doppler imaging for identifying active phases of brucellosis. Method Ninety patients diagnosed with brucellosis from August 2023 to April 2024 at the Second Hospital of Hohhot were included in the study. Based on the presence of fever and laboratory findings, they were divided into an acute episode group and a non-acute episode group. All cases underwent musculoskeletal ultrasound with color Doppler imaging to observe blood flow signals in tendons and surrounding synovial membranes. Statistical analyses were conducted to compare the groups. Result The acute episode group included 56 patients (62.2%), of whom 19 (33.9%) showed increased blood flow signals, while 37 (66.1%) had no significant blood flow signals. In the non-acute episode group of 34 patients (37.8%), 4 (11.8%) exhibited increased blood flow signals, while 30 (88.2%) showed no significant signals. Chi-square tests revealed a significant difference in the imaging characteristics between the two groups, with statistical significance (P=0.019). Correlation testing using the Phi coefficient yielded a value of 0.246, indicating a moderate positive correlation with statistical significance (P=0.019). Logistic regression analysis revealed that the likelihood of patients with increased blood flow signals being in the acute phase was 3.851 times higher than those without significant blood flow signals, with a statistically significant relationship (P=0.025). Conclusion Increased blood flow signals in tendons or surrounding synovial membranes are moderately correlated with acute episodes of brucellosis. These findings can complement other clinical diagnostic indicators, making musculoskeletal ultrasound with color Doppler imaging a promising auxiliary tool for assessing active phases of brucellosis. This technique may provide clinicians with more accurate diagnostic and management strategies.

Key words: Brucellosis, Musculoskeletal ultrasound, Inflammatory activity indicator, Soft tissue blood flow signals

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