Abstract: Objective To investigate the application value of MRI IDEAL-IQ imaging technology in the diagnosis of hepatic fibrosis and early cirrhosis of hepatitis B virus and to explore a new and simple imaging method to evaluate hepatic fibrosis and early cirrhosis. Methods A total of 229 patients with hepatitis B and liver fibrosis diagnosed with hepatic puncture and histology from Shenzhen Third People's Hospital from October 2019 to May 2021 were selected and divided into four groups according to the classification and staging criteria of chronic hepatitis: S1 stage (105 cases), S2 stage (51 cases), S3 stage (41 cases), S4 stage (32 cases), the imaging data of four groups of patients (IDAEL-IQ R2* relaxation rate value, ultrasound elastography STE Value) and laboratory examination data (serological examination: hyaluronic acid, procollagen Ⅲ, collagen Ⅳ, laminin). Compare the imaging and laboratory measurement data of the four groups of patients; analyze the correlation between IDAEL-IQ R2* value and ultrasound elastography STE value and serological indicators; use ROC curve to evaluate the diagnostic efficacy of IDAEL-IQ R2* value . Results ①The R2* value of the S4 group was significantly different from the other three groups (S1, S2, S3) (P=0.001, P<0.001, P=0.041), while the S1, S2, and S3 groups There was no statistically significant difference in R2* value between the two groups (P=1.000, P=1.000, P=0.720). ②The R2* value was significantly positively correlated with the ultrasound STE value and hyaluronic acid (r=0.203, P=0.004; r=0.245, P<0.001). ③The area under the ROC curve for the diagnosis of early liver cirrhosis by R2* value is 0.747, the sensitivity and specificity are 0.818 and 0.619, respectively, and the diagnostic cut-off value is 51.05sec-1. Conclusion There were statisticallysignificant difference between the R2* value in the early stage of liver cirrhosis (S4) and the advanced stage of liver fibrosis (S1, S2, S3) in patients with hepatitis B, and can be used as a new technique for the diagnosis of early liver cirrhosis and liver fibrosis in patients with viral hepatitis B.

Key words: Brain parenchymal tuberculoma, Magnetic resonance imaging, Enhancement