Abstract: Objective To investigate the manifestations of MRI-DWI and ultrasound in prostate tuberculosis. Methods 3 patients with clinically diagnosed prostate tuberculosis from January 2014 to December 2018 were collected, including 1 patient with bilateral seminal vesicle tuberculosis. The imaging manifestations of ultrasound and MRI were retrospectively analyzed to explore the characteristic manifestations of ultrasound, MRI and DWI in the diagnosis of prostate tuberculosis. Results The diagnosis was confirmed by the pathology of prostate biopsy in 1 of the 3 patients, while prostatic fluid tuberculous bacilli culture was positive in the remaining 2 cases. Ultrasound examination revealed that the prostate lesions of 3 patients were located in the external gland area and the internal gland area, mainly with hypo-echogenicity, occasionally with mixed echogenicity.Abundant color blood flow around the lesions was also detected on color doppler. MRI findings included heterogeneous signal intensity in prostate signal and tuberculosis nodules with T1 isointense signal, T2 slightly high signal and obviously restricted diffusion on DWI. In addition, tuberculosis granuloma was shown as nodular T2 low signal, T1 iso-intenseor slightly lower signal, low signal on DWI, and the ADC value of (1.08-1.10)×10^-3mm²/s. Conclusion Ultrasound, MRI and DWI could show certain characteristics for tuberculous granuloma of prostate tuberculosis, which provides evidence for clinical diagnosis tuberculosis granuloma.

Key words: Prostate, Tuberculous granuloma, Ultrasound, Magnetic resonance imaging, Diffusion weighted imaging