Abstract: Objective This article explores a new hepatitis C management model by presenting the current status, Objectives, methods, and outcomes of full-course management at Shenyang Sixth People's Hospital, offering a reference for clinical practice. Method According to the "HCV full-course management model", the HCV high-risk group should receive regular screening, and Anti-HCV positive patients were recommended to undergo HCV RNA tests. Authorized physicians determine therapeutic regimen, follow up HCV infected patients, and enter screening, treatment, and follow-up information into "HCV Prevention and Control Information System of the Chinese Center for Disease Control and Prevention Information System". The advancement and feasibility of the "full-course management model" were evaluated and compared based on treatment rate, follow-up rate, the sustained virological response (SVR) rate, etc. Result During the one-year implementation of the whole-course management of hepatitis C in our hospital, through continuous optimization of the work process, the new discovery rate, diagnosis rate and treatment rate of hepatitis C have been increased, and the data has become statistically available. After the implementation, the number of newly diagnosed hepatitis C patients increased by 84% compared with that before the implementation, the HCV RNA detection rate of the patients was 100%, and the treatment rate was 83.26%, among the patients followed up after treatment, the rapid virological response (RVR) rate reached 97.67%. The early virological response (EVR) rate reached 83.46%, the SVR rate reached 90.48%. The quantification of hepatitis C diagnosis and treatment data has been realized, filling the gap in previous data management of our hospital and laying a foundation for the improvement of the whole-course management of hepatitis C in the future. Conclusion By strengthening the organizational management, screening, and follow-up management aspects of the full-course management of hepatitis C, patient treatment adherence was improved, leading to an increase in diagnosis and cure rates, and a reduction in the risk of new infections and mortality.

Key words: Hepatitis C, Total course management, Treatment compliance, Diagnosis rate, Cure rate