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新发传染病电子杂志 ›› 2024, Vol. 9 ›› Issue (5): 94-97.doi: 10.19871/j.cnki.xfcrbzz.2024.05.018

• 标准/指南/共识 • 上一篇    下一篇

《人感染禽流感诊疗方案(2024年版)》解读

韩冰, 蒋荣猛   

  1. 北京市感染性疾病质量控制和改进中心,首都医科大学附属北京地坛医院感染中心,北京 100015
  • 收稿日期:2024-06-25 出版日期:2024-10-31 发布日期:2024-12-11
  • 通讯作者: 蒋荣猛,Email:13911900791@163.com
  • 基金资助:
    1.2024年首都卫生发展科研专项(首发2024-1-2172); 2.北京市高层次公共卫生技术人才建设项目学科带头人(2022-学科带头人-01-02)

Interpretation of the Diagnosis and treatment scheme for human infection with avian influenza virus (2024 Edition)

Han Bing, Jiang Rongmeng   

  1. Beijing Center for Quality Control and Improvement of Infectious Diseases, Diagnosis and Treatment Center of Infectious Diseases, Beijing Ditan Hospital, Capital Medical University, Beijing 100015, China
  • Received:2024-06-25 Online:2024-10-31 Published:2024-12-11

摘要: 禽流感(avian influenza)是一种由甲型禽流感病毒引起的动物传染病,主要影响禽类,也可感染哺乳动物,并在人类中偶有散发病例。人感染禽流感是一种由某些亚型禽流感病毒引起的急性呼吸道传染病,具有较高的病死率和医疗负担。为规范人感染禽流感的诊疗工作,国家卫生健康委员会制定了《人感染禽流感诊疗方案(2024年版)》。本文基于该诊疗方案,从疾病命名、早期识别、病原学诊断、规范治疗和多学科协作等方面进行了解读,强调了疾病的统一命名为“人感染禽流感”,以及流行病学史在早期诊断中的重要性。此外,本文还探讨了核酸检测作为确诊标准的必要性,介绍了新型抗病毒药物的应用,指出了糖皮质激素治疗的潜在风险,呼吁规范抗菌药物的使用,并提出了重症病例救治时多学科协作的重要性。通过这些措施,旨在提高诊疗质量,降低重症率和病死率。

关键词: 禽流感, 人感染禽流感, 诊疗方案, 解读

Abstract: Avian influenza is a zoonotic disease caused by the influenza A virus, primarily affecting birds but also capable of infecting mammals, with sporadic cases in humans. Human infection with avian influenza is an acute respiratory disease caused by certain subtypes of the avian influenza virus, associated with high mortality rates and significant healthcare burdens. To standardize the diagnosis and treatment of human infections with avian influenza, the National Health Commission has developed the Diagnosis and Treatment Plan for Human Infection with Avian Influenza (2024 Edition). This paper provides an analysis of the plan, addressing key aspects such as disease nomenclature, early identification, etiological diagnosis, standardized treatment, and multidisciplinary collaboration. It emphasizes the importance of a unified disease nomenclature under "human infection with avian influenza" and the critical role of epidemiological history in early diagnosis. Additionally, the paper discusses the necessity of nucleic acid testing as the definitive diagnostic standard, introduces new antiviral therapies, highlights the potential risks associated with corticosteroid use, advocates for the appropriate use of antibiotics, and underscores the importance of multidisciplinary collaboration in managing severe cases. These measures are aimed at improving the quality of diagnosis and treatment, thereby reducing the severity and mortality rates associated with human infections with avian influenza.

Key words: Avian influenza, Human infection with avian influenza virus, Diagnosis and treatment scheme, Interpretation

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